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. Author manuscript; available in PMC: 2021 Jun 15.
Published in final edited form as: Cancer. 2020 Mar 10;126(12):2821–2828. doi: 10.1002/cncr.32811

Table 1.

Patient and tumor characteristics at baseline for all eligible patients.

Bevacizumab + Placebo (n=58) Bevacizumab + Trebananib (n=57)
Patient or Tumor Characteristic n % n %
Age (years)
 Median 58 57
 Min - Max 22 - 79 30 - 80
 < 50 17 29.3 14 24.6
 ≥50 41 70.7 43 75.4
Gender
 Male 36 62.1 32 56.1
 Female 22 37.9 25 43.9
Race
 Asian 2 3.4 0 0.0
 Black or African American 3 5.2 2 3.5
 White 53 91.4 53 93.0
 Unknown or not reported 0 0.0 2 3.5
Ethnicity
 Hispanic or Latino 3 5.2 2 3.5
 Not Hispanic or Latino 55 94.8 54 94.7
 Unknown 0 0.0 1 1.8
Karnofsky Performance Status
 70-80 31 53.4 34 59.6
 90-100 27 46.6 23 40.4
Neurologic Function
 No symptoms 12 20.7 11 19.3
 Minor symptoms 32 55.2 27 47.4
 Moderate symptoms (fully active) 10 17.2 16 28.1
 Moderate symptoms (required assistance) 4 6.9 3 5.3
Surgery (Initial Brain Tumor)
 Biopsy only 8 13.8 3 5.3
 Subtotal resection 19 32.8 12 21.1
 Gross total resection 30 51.7 42 73.7
 Other 1 1.7 0 0.0
Recent resection
 No/biopsy only 30 51.7 30 52.6
 Yes 28 48.3 27 47.4
Histologic Tumor Type
 Glioblastoma 53 91.4 53 93.0
 Gliosarcoma 2 3.4 2 3.5
 Glioblastoma with Oligodendroglial Features 2 3.4 1 1.8
 Giant Cell Glioblastoma 0 0.0 1 1.8
 Other 1 1.7 0 0.0