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POL II Ser2P, serine 2 phosphorylated POLR2A (transcription elongation complex); POL II Ser5P, serine 5 phosphorylated POLR2A (transcription initiation complex); pA1, proximal poly(A) site; pA2, distal poly(A) site; black lollipops between pA1 and pA2, methylated CpG dinucleotides
