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. Author manuscript; available in PMC: 2021 Jun 1.
Published in final edited form as: Clin Perinatol. 2020 Feb 20;47(2):399–412. doi: 10.1016/j.clp.2020.02.002

Figure 1. Potential mechanisms that may explain the intestinal inflammation or injury resulting from anemia and RBC transfusion.

Figure 1.

Abbreviations: ET1, endothelin 1; NO, nitric oxide; Th, T helper cell; TLR-4, toll-like receptor 4. Adapted from Saroha V, Josephson CD, Patel RM. Epidemiology of Necrotizing Enterocolitis: New Considerations Regarding the Influence of Red Cell Transfusions and Anemia. Clin Perinatol. 2019 Mar;46(1):101–117; with permission.