. Author manuscript; available in PMC: 2020 May 24.

Published in final edited form as: Heart Fail Rev. 2013 Jan;18(1):79–94. doi: 10.1007/s10741-012-9332-0

Table 8.

Univariate meta-regression results for peak VO₂ and VE/VCO₂ slope

Variables	Peak VO₂ p value	VE/VCO₂ slope p value

Mean LVEF (%)	.79	.64
Mean NYHA (I-IV)	.53	.75
Mean age (years)	.50	.72
Male (%)	.38	.71
Ischemic cardiomyopathy (%)	.84	.71
Beta-blockers (%)	.06	.65
Study sample size	.40	.21
Study quality	.42	.97
Threshold	.06	.20

Univariate meta-regression could not be performed on OUES and EOB due to limited studies and model saturation, respectively VO₂ oxygen consumption, VE/VCO₂ minute ventilation/carbon dioxide production, LVEF left ventricular ejection fraction, NYHA New York Heart Association