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. 2020 May 24;15:51. doi: 10.1186/s13020-020-00326-w

Table 3.

Major chemical constituents and possible targets of TCM in COVID-19

Major chemical constituents Possible targets References
HXZQ Quercetin, isorhamnetin, irisolidone, kaempferol, wogonin, baicalein PTGS2, HSP90AB1, CAMSAP2 [5, 6]
LHQW Kaempferol, quercetin, glycyrrhetinic acid, stigmasterol, indigo SARS-CoV-2 3CL (Mpro), ACE2, MAPK, PI3K-AKT, NF-κB [8]
SFJD Quercetin, kaempferol, luteolin IL-6, ALB, MAPK3 [18]
XBJ Hydroxysafflor yellow A, chlorogenic acid, salvianolic acid B NF-κB, HIF-1, VEGF [21]