Table 1.
Baseline characteristics of the study population in relation to ICU mortality
| Survivors, N = 134 | Non-survivors, N = 88 | p | |
|---|---|---|---|
| Age (years) | 60 [43–70] | 64 [54–75] | 0.005 |
| Female, N (%) | 38 (31%) | 31 (35%) | 0.48 |
| BMI (kg/m2) | 24.85 [22.67–28.28] | 24.25 (22.29–29.02) | 0.97 |
| ARDS category, N (%) | 0.001 | ||
| • Mild | 32 (24) | 9 (10) | |
| • Moderate | 90 (67) | 50 (57) | |
| • Severe | 12 (9) | 29 (33) | |
| Cause of ARDS, N (%) | 0.04 | ||
| • Pulmonary | 76 (57) | 37 (42) | |
| • Extrapulmonary | 58 (43) | 51 (58) | |
| PaO2/FiO2 | 195 [146–231] | 153 [115.33–189.28] | 0.001 |
| PaCO2 (mmHg) | 40 [35.92–4] | 44.45 [39.15–52.9] | 0.001 |
| Respiratory rate (bpm) | 16 (13–20) | 17.5 (14–20) | 0.07 |
| Tidal volume (mL) | 510 [450–600] | 480 [420–550] | 0.004 |
| Tidal volume/body weight (mL/kg) | 7.93 [7–9.1] | 7.82 [6.7–8.47] | 0.12 |
| Clinical PEEP (cmH2O) | 10 [10–12.5] | 10 [10–12] | 0.68 |
| Driving pressure (cmH2O) | 12.58 ± 3.31 | 14.03 ± 3.48 | 0.004 |
| Respiratory system elastance (cmH2O/mL) | 23.91 [18.44–29.15] | 28.57 [22.97–34.87] | 0.001 |
| SAPS II | 36 [29–47] | 44 [37.75–56] | 0.001 |
| Intensive care unit stay (days) | 19.5 [11.5–30.5] | 15 [8–24] | 0.009 |
Quantitative data are expressed as mean (standard deviation, SD) or median [interquartile range] as appropriate. Categorical data are presented as N (number of subjects) and percentages (%). Student’s t test or Wilcoxon-Mann-Whitney test, as appropriate, were used for continuous variable analysis, while chi-squared test were used for categorical variable analysis
BMI body mass index, ARDS acute respiratory distress syndrome, SAPS Simplified Acute Physiology Score
Italicized data are for statistically significant results