Table 4.

Multivariable regression models investigating risk factors for ICU mortality in ARDS patients

ICU mortality	RR	95% CI	p	ICU mortality	RR	95% CI	p
Age (with each 1-year increase)	1.01	1.00 - 1.02	0.041	Age (with each 1-year increase)	1.01	1.01- 1.02	0.024
SAPS II (with each 1-point increase)	1.01	1.00 - 1.02	0.004	SAPS II (with each 1-point increase)	1.01	1.01- 1.02	0.007
100 < PaO2 / FiO2 ≤ 200	1.47	0.74 - 2.94	0.274	100 < PaO2 / FiO2 ≤ 200	1.32	0.66- 2.64	0.438
PaO2 / FiO2 ≤ 100	2.95	1.48 - 5.89	0.002	PaO2 / FiO2 ≤ 100	2.80	1.40- 5.56	0.003
Transpulmonary MP_PBW (J/min/Kg)	1.68	0.48 - 5.93	0.419	Transpulmonary MP_well inflated tissue(J/min/g)	3.01	1.15- 7.91	0.025
ICU mortality	RR	95% CI	p	ICU mortality	RR	95% CI	p
Age (with each 1-year increase)	1.01	1.00 - 1.03	0.024	Age (with each 1-year increase)	1.01	1.00 - 1.03	0.019
SAPS II (with each 1-point increase)	1.01	1.00 - 1.02	0.008	SAPS II (with each 1-point increase)	1.01	1.00 - 1.02	0.009
100 < PaO2 / FiO2 ≤ 200	1.44	0.72 - 2.88	0.300	100 < PaO2 / FiO2 ≤ 200	1.31	0.65 - 2.63	0.444
PaO2 / FiO2 ≤ 100	2.85	1.42 - 5.70	0.003	PaO2 / FiO2 ≤ 100	2.78	1.39 - 5.54	0.004
Transpulmonary MP_CRS (J/min/mL/cmH2O)	1.74	1.11 - 2.70	0.015	Transpulmonary MP_lung gas volume (J/min/g)	1.00	0.99 - 1.01	0.157

Relative risk (RR) and 95% confidence intervals (CI) of intensive care unit (ICU) mortality calculated with multivariable Poisson regression models with robust standard error

Effects of age (years), SAPS II (reference: SAPS II simplified acute physiology score), ARDS severity (PaO₂/FiO₂; reference > 200), transpulmonary mechanical power normalized to predicted body weight (Transpulmonary MP_PBW), transpulmonary mechanical power normalized to well inflated tissue (Transpulmonary MP_well inflated tissue), transpulmonary mechanical power normalized to respiratory system compliance (Transpulmonary MP_CRS), transpulmonary mechanical power normalized to lung gas volume (Transpulmonary MP_lung gas volume)