Table 3.
Some GC—MS identified bioactive compounds of the hexane fraction of C. crepidioides leaf extract that may be responsible for observed activities.
| S/N | Retention time (mins) | Name of compound (library ID) | Molecular formula | Peak area (%) | Reported biological activity |
|---|---|---|---|---|---|
| 1 | 3.586 | Butyrolactone | C4H6O2 | 0.98 | Antimicrobial. Central nervous system depressant (CNS) and hypnotic. Anaesthetic. |
| 2 | 5.449 | Benzene acetaldehyde | C8H8O | 1.11 | Antioxidant antibacterial, anaesthetic. |
| 3 | 5.568 | 1-methyl, 2-Pyrrolidinone | C5H9NO | 2.69 | Surfactant, antifungal antioxidant, antibacterial anticancer, anticonvulsant. |
| 4 | 10.286 | Benzofuran | C8H6O | 1.43 | Antidepressant, anticancer, antiviral, antifungal, antioxidant, antipsychotic, anti-inflammatory. |
| 5 | 13.640 | Thujone | C10H16O | 0.56 | Antiplatelet antibacterial, antifungal, antinociceptive, insecticidal, anthelmintic antioxidant. |
| 6 | 14.180 | Eugenol | C10H12O2 | 4.43 | Anti-inflammatory, antiseptic, antiaggregant. |
| 7 | 19.795 | Benzofuranone | C8H6O | 2.99 | Antioxidant, anticancer |
| 8 | 22.151 | 1,9-octadecadiene | C18H34 | 0.78 | Not stated |
| 9 | 24.816 | Orcinol | C7H8O2 | 3.14 | Antifungal, antimicrobial, and keratolytic. |
| 10 | 26.704 | Hexadecanoic acid, methyl ester | C17H34O2 | 1.48 | Antioxidant, hypocholesterolemic, nematicide, Pesticide, antiandrogenic, flavor, hemolytic, 5-alpha reductase inhibitor. |
| 11 | 27.250 | n-Hexadecanoic acid | C16H32O2 | 1.19 | Antioxidant, anti-inflammation hypocholesterolemic, nematicide Pesticide, Lubricant, antiandrogenic, flavor, hemolytic, 5-alpha reductase inhibitor. |
| 12 | 28.816 | 7,10,13-Hexadecatrienoic acid, methyl ester | C20H36O3 | 5.74 | Antibacterial, antifungal. |
| 13 | 29.404 | 9,12,15-Octadecatrienoic acid (α-linolenic acid) | C18H30O2 | 4.52 | Anti-inflammatory, Hypolipidemic, antiaggregant, Antileukotriene, antiprostatic, immunostimulant, vasodilator, 5-alpha reductase inhibitor. |