Figure 2.

Gene expression analysis. RNA was isolated from the liver of different samples and was used to measure mRNA levels of different genes in each group (a–g) using Quantitative RT-QPCR. Data are presented as mean ± SD. Comparison between the control group and the sorafenib group is presented by ^∗, where ^∗P < 0.05, while ^∗∗P < 0.01. SORA: sorafenib; BAX: Bcl-2 Associated X; BID: BH3 interacting-domain death agonist; NF-κB-p65: Nuclear factor kappa B; Bcl-2: B-cell lymphoma-2; GPX-1: Glutathione peroxidase-1; HO-1: Heme Oxygenase-1; SOD2: superoxide dismutase-2.