Table 3.
Univariate and multivariate analyses of TERT promoter mutations.
Univariate | Multivariate | |||
---|---|---|---|---|
OR (95% CI) | p value | OR (95% CI) | p value | |
Age | 1.04 (1.00, 1.08) | 0.038 | 1.06 (1.01, 1.12) | 0.025 |
Gender | 0.78 (0.33, 1.85) | 0.571 | ||
Grade | 1.89 (0.76, 4.72) | 0.173 | ||
Side | 2.00 (0.33, 12.18) | 0.452 | ||
Location | 2.19 (0.30, 15.85) | 0.437 | ||
NeV | 1.38 (0.80, 2.35) | 0.245 | ||
EnV | 0.99 (0.93, 1.05) | 0.712 | ||
EdV | 1.04 (0.98, 1.11) | 0.197 | ||
CNV (%) | 1.15 (1.09, 1.22) | <0.001 | 1.12 (1.06 1.18) | <0.001 |
ONV (%) | 1.04 (0.98, 1.10) | 0.196 | ||
Cho/NAA | 0.96 (0.82, 1.14) | 0.668 | ||
Cho/Cr | 1.48 (1.04, 2.09) | 0.028 | 2.71 (1.15, 3.25) | 0.012 |
Lip | 1.25 (0.52, 2.99) | 0.616 | ||
Lac | 2.69 (1.12, 6.43) | 0.026 | 3.14 (1.01, 9.74) | 0.048 |
Radscore | 2.72 (1.78, 4.14) | <0.001 | 2.04 (1.51, 2.77) | <0.001 |
OR: odds ratios; CI: confidence intervals; NeV: necrotic volume of tumor; EnV: volume of enhanced portion of tumor; EdV: volume of edema around tumor; CNV: necrotic volume percentage of core; ONV: necrotic volume percentage of overall; Cho/NAA: the ratio of N-acetylaspartic acid to creatine in MRS; Cho/Cr: the ratio of choline to creatine in MRS; Lip: lipid peak of MRS; Lac: lactate peak of MRS; Radscore: radiomics feature. p value <0.05 was considered significant difference.