Table-1.
Indicators of structural and functional remodeling of the left ventricular myocardium in dogs with endocardial mitral valve, depending on the functional class of chronic heart failure.
| Marker | Clinically healthy dogs (n=36) | Sick dogs with the appropriate functional class of heart failure | |||
|---|---|---|---|---|---|
| I (n=38) | II (n=32) | III (n=27) | IV (n=11) | ||
| LVM, g | 49.6±2.05 | 49.8±1.58 | 62.1±1.75* | 65.2±1.77* | 80.1±3.27* |
| LVMMI, g/m2 | 121.9±3.90 | 132.0±7.21 | 172.6±8.88* | 162.2±7.50* | 191.1±10.93* |
| GSIs, RU/ml | 0.59±0.005 | 0.58±0.005 | 0.61±0.006* | 0.65±0.011* | 0.70±0.026* |
| GSId, RU/ml | 0.53±0.005 | 0.53±0.005 | 0.58±0.009* | 0.63±0.012* | 0.71±0.020* |
| RMTd, RU/ml | 0.65±0.015 | 0.64±0.015 | 0.68±0.011 | 0.64±0.019 | 0.64±0.018 |
| RMTs, RU/ml | 1.3±0.03 | 1.3±0.03 | 1.5±0.03* | 1.2±0.04* | 0.9±0.04* |
| ISRI, RU/ml | 126.1±2.39 | 127.1±3.36 | 123.6±3.27 | 91.8±4.84* | 53.9±4.71* |
Numerator—M±m, Denominator—Lim;
*
Significant difference compared with the control group (p<0.05). GSIs=Gonadosomatic indices, LVM=Left ventricular mass, LVMMI=Left ventricular mass index, ISRI=Integral systolic remodeling index