Table 3.

Cox regression of baseline values in uni- and multivariate (*) analysis

Baseline values	Whole cohort		PAH		PAH with comorbidities
	Cox regression	n	Cox regression	n	Cox regression	n
	p-value		p-value		p-value
Survival
6MWD	< 0.0001	137	0.006	65	0.052	42
NT-proBNP	0.006	102	0.011	63	0.356	37
WHO-FC	0.005*	121	0.001*	74	0.403	46
RA area	0.254	133	0.991	82	0.472	49
RV area	0.778	135	0.631	84	0.505	49
TAPSE	0.006	137	0.033	86	0.220	49
LV-EI	0.613	111	0.896	72	0.282	38
RV pump function	< 0.0001	109	< 0.0001	85	0.499	49
Time to clinical worsening
6MWD	< 0.0001*	109	0.02	65	0.047*	44
NT-proBNP	0.024	102	0.07	63	0.485	39
WHO-FC	0.001	122	< 0.0001*	74	0.346	48
RA area	0.002	133	0.067	82	0.074	51
RV area	0.017	135	0.073	84	0.342	51
TAPSE	0.049	137	0.071	86	0.679	51
LV-EI	0.096	111	0.398	72	0.065	39
RV pump function	< 0.0001*	135	< 0.0001	84	0.344	51

6MWD 6-min walking distance, NT-proBNP: n-terminal pro brain natriuretic peptide, WHO-FC World Health Organization Functional Class, RA right atrial, RV right ventricular, TAPSE tricuspid annular plane systolic excursion, LV-EI left ventricular eccentricity index. Parameters that were used for multivariate analysis are written in bold. *Denotes significant parameters in multivariate analysis