Table 4.
The functional analyses of survival-related genes
| Category | Term | Count | P value | FDR |
|---|---|---|---|---|
| GO-BP | GO:0002250~adaptive immune response | 28 | 6.430E-13 | 1.560E-09 |
| GO:0050776~regulation of immune response | 28 | 5.700E-11 | 6.900E-08 | |
| GO:0070098~chemokine-mediated signaling pathway | 18 | 1.450E-10 | 1.170E-07 | |
| GO:0006955~immune response | 41 | 3.820E-09 | 1.850E-06 | |
| GO:0042110~T cell activation | 14 | 3.170E-09 | 1.920E-06 | |
| GO:0006935~chemotaxis | 19 | 1.430E-07 | 5.750E-05 | |
| GO:0006954~inflammatory response | 35 | 2.300E-07 | 7.950E-05 | |
| GO:0006968~cellular defense response | 13 | 9.040E-07 | 2.730E-04 | |
| GO:0007267~cell-cell signaling | 26 | 1.760E-06 | 4.740E-04 | |
| GO:0007166~cell surface receptor signaling pathway | 27 | 2.180E-06 | 5.280E-04 | |
| GO:0071346~cellular response to interferon-gamma | 11 | 1.840E-05 | 4.037E-03 | |
| GO:0042102~positive regulation of T cell proliferation | 11 | 2.930E-05 | 5.894E-03 | |
| GO:0007204~positive regulation of cytosolic calcium ion concentration | 16 | 4.730E-05 | 8.769E-03 | |
| GO:0035589~G-protein coupled purinergic nucleotide receptor signaling pathway | 6 | 6.700E-05 | 1.152E-02 | |
| GO:0043547~positive regulation of GTPase activity | 38 | 9.630E-05 | 1.446E-02 | |
| GO:0070374~positive regulation of ERK1 and ERK2 cascade | 18 | 9.260E-05 | 1.484E-02 | |
| GO:0007155~cell adhesion | 32 | 2.060E-04 | 2.894E-02 | |
| GO:0007165~signal transduction | 63 | 2.210E-04 | 2.926E-02 | |
| GO:0048247~lymphocyte chemotaxis | 7 | 2.880E-04 | 3.606E-02 | |
| GO:0042472~inner ear morphogenesis | 9 | 3.260E-04 | 3.873E-02 | |
| GO:0050850~positive regulation of calcium-mediated signaling | 6 | 4.390E-04 | 4.712E-02 | |
| GO:0006508~proteolysis | 33 | 4.240E-04 | 4.774E-02 | |
| GO:0002548~monocyte chemotaxis | 8 | 4.660E-04 | 4.781E-02 | |
| KEGG Pathway | hsa04060:Cytokine-cytokine receptor interaction | 38 | 4.250E-12 | 9.690E-10 |
| hsa04080:Neuroactive ligand-receptor interaction | 34 | 4.100E-08 | 4.680E-06 | |
| hsa04640:Hematopoietic cell lineage | 17 | 4.960E-07 | 3.770E-05 | |
| hsa04514:Cell adhesion molecules (CAMs) | 19 | 2.440E-05 | 1.389E-03 | |
| hsa04062:Chemokine signaling pathway | 21 | 9.560E-05 | 4.350E-03 | |
| hsa04660:T cell receptor signaling pathway | 13 | 9.200E-04 | 2.590E-02 | |
| hsa05033:Nicotine addiction | 8 | 1.213E-03 | 3.028E-02 | |
| hsa04650:Natural killer cell mediated cytotoxicity | 14 | 1.739E-03 | 3.543E-02 |
KEGG Kyoto Encyclopedia of Genes and Genomes, FDR false discovery rate, GO-BP Gene Ontology-Biology Process