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. 2020 May 24;15:108. doi: 10.1186/s13019-020-01140-z

Table 5.

Deterministic sensitivity and probabilistic analysis

Deterministic sensitivity analysis LCO incidence Cost per patient (€) Mean ICU stay per patient (days) Mean PO ward stay per patient (days) Patients with no complications
(% of total)
Intervention (Levosimendan) Base case 14,792.33 2.50 6.46 53.85
LCO 18% [4] 14,562 [13,741-14,879] 2.35 [1.8–3] 6.22 [5.7–7.8] 55.01 [52.87–57.87]
LCO 6% [17] 12,757 [12,172-14,892] 2.07 [1.4–2.3] 5.63 [4.9–7.5] 61.23 [55.69–68.71]
No intervention Base case 17,006.94 5.70 6.40 31.71
LCO 35% [16] 16,511 [15,061- 16,773] 5.3 [4.1–6.9] 6.1 [4.9–6.5] 35.22 [32.6–38.03]
LCO 25% [4] 15,825 [14,988- 16,260] 4.8 [3.5.-5.7] 5.9 [4.8–6.3] 38.6 [35.7–41.32]
Probabilistic analysis Cost per patient (€) Mean ICU stay (days)

Mean PO

ward stay (days)

Patients with no complications (% of total)
Intervention (Levosimendan) 14,401 [13,368-14,971] 2.39 [1–3.9] 6.23 [4.2–8.34] 51.8 [47.34–53.02]
No intervention 16,652 [16,004- 17,212] 5.4 [3.8–7.1] 6.17 [4.03–8.22] 29.98 [27.91–32.4]
Difference 2251

€: euro, LCO: Low Cardiac Output, PO: postoperative, ICU: Intensive Care Unit, [95% CI]

[4] Ref. 4 (Mehta RH at al.) [16]. Ref 16 (Pieri M et al.) [17]. Ref 17 (Desai PM et al.)