Table 2. DEGs of bEnd.3 cells between the two groups.
Different expression genes of bEnd.3 cells between the infection and mock-infection group.
| Components | Genes | log2 | padj | Description | |
|---|---|---|---|---|---|
| Fold change | |||||
| DEGs related to cell junctional complexes | |||||
| Tight junctions (TJs) | Claudins | Cldn5 | −0.51506 | 0.000166 | claudin 5 |
| Adherens junctions (AJs) | Cadherin | Cdh5 | −0.73355 | 3.27E−19 | cadherin 5 |
| Cdh24 | −0.78667 | 0.041049 | cadherin-like 24 | ||
| nectin | Nectin1 | −1.7466 | 1.22E−50 | nectin cell adhesion molecule 1 | |
| Nectin2 | −0.53373 | 0.00102 | nectin cell adhesion molecule 2 | ||
| Nectin3 | 0.59157 | 3.14E−07 | nectin cell adhesion molecule 3 | ||
| DEGs related to actin cytoskeletal rearrangements | |||||
| Regulation of actin cytoskeleton | Cfl1 | −0.54554 | 3.27E−10 | cofilin 1, non-muscle | |
| Actn1 | −0.60337 | 2.06E−09 | actinin, alpha 1 | ||
| Limk1 | −0.6284 | 0.001253 | LIM-domain containing, protein kinase | ||
| Pxn | −0.83324 | 3.61E−10 | paxillin | ||
| Actn4 | −1.6743 | 1.54E−27 | actinin alpha 4 | ||
| Actb | 2.0004 | 1.10E−136 | actin, beta | ||
| Itgav | 0.78575 | 1.76E−21 | integrin alpha V | ||
| Rock1 | 0.61447 | 2.59E−12 | Rho-associated coiled-coil containing protein kinase 1 | ||
| Rock2 | 0.50308 | 2.05E−09 | Rho-associated coiled-coil containing protein kinase 2 | ||
| DEGs of immune activation and inflammatory response | |||||
| Pattern recognition receptors (PRRs) | Tlr13 | 1.2499 | 6.48E−16 | toll-like receptor 13 | |
| Tlr4 | 0.82039 | 2.48E−17 | toll-like receptor 4 | ||
| Complement system | C3 | −0.58759 | 0.005068 | complement component 3 | |
| C3ar1 | 0.74408 | 2.90E−05 | complement component 3a receptor 1 | ||
| Cfp | −0.99477 | 3.44E−05 | complement factor properdin | ||
| Masp1 | 3.9332 | 0.00077 | mannan-binding lectin serine peptidase 1 | ||
| Chemokines | C subfamiliy | Xcr1 | 1.749 | 6.96E−06 | chemokine (C motif) receptor 1 |
| C–C subfamiliy | Ccl2 | 0.61885 | 0.000328 | chemokine (C–C motif) ligand 2 | |
| Ccrl2 | 0.72992 | 0.03855 | chemokine (C–C motif) receptor-like 2 | ||
| C–X3–C subfamiliy | Cx3cl1 | −0.54859 | 0.000456 | chemokine (C–X3–C motif) ligand 1 | |
| C–X–C subfamiliy | Cxcl1 | 1.7688 | 2.22E−06 | chemokine (C–X–C motif) ligand 1 | |
| Cxcl16 | 1.4227 | 0.000779 | chemokine (C–X–C motif) ligand 16 | ||
| Cxcl2 | 1.7977 | 0.00055 | chemokine (C–X–C motif) ligand 2 | ||