Table 3. DEGs of APEC strain between two groups.
Different expression genes of APEC strain between the infection and mock-infection group.
| Components | Gene name |
log2 Fold Change |
padj | Description | |
|---|---|---|---|---|---|
| Virulence factors related to meningitis | |||||
| Outer membrane protein | CXG97_RS20855 | – | −2.3638 | 3.43E−06 | membrane protein |
| CXG97_RS13750 | – | −1.8361 | 0.0083262 | membrane protein | |
| CXG97_RS15480 | – | −1.7665 | 0.014095 | membrane protein | |
| CXG97_RS10635 | – | −1.1948 | 0.039525 | membrane protein | |
| CXG97_RS12085 | – | 3.121 | 3.42E−09 | membrane protein | |
| CXG97_RS18795 | – | 1.5797 | 0.003432 | membrane protein | |
| CXG97_RS10035 | – | 1.1784 | 0.032157 | membrane protein | |
| CXG97_RS08525 | – | 1.3149 | 0.015745 | autotransported outer membrane protein involved in cell adhesion | |
| CXG97_RS01930 | – | 1.7816 | 0.0014647 | autotransporter outer membrane beta-barrel domain-containing protein | |
| CXG97_RS01635 | – | 1.4776 | 0.0098823 | autotransporter outer membrane beta-barrel domain-containing protein | |
| CXG97_RS09010 | – | 1.6293 | 0.049761 | fimbrial biogenesis outer membrane usher protein | |
| CXG97_RS18505 | – | 1.3315 | 0.045966 | fimbrial biogenesis outer membrane usher protein | |
| CXG97_RS09580 | slyB | 1.3411 | 0.0099186 | outer membrane lipoprotein SlyB | |
| CXG97_RS15430 | – | 1.5911 | 0.0023044 | outer membrane protein assembly factor BamD | |
| CXG97_RS15540 | – | 1.2863 | 0.015568 | outer membrane protein assembly factor BamE | |
| fimbrial | CXG97_RS01490 | – | −3.3352 | 2.07E−05 | fimbrial chaperone EcpB |
| CXG97_RS17665 | – | −1.2869 | 0.0229 | fimbrial protein SteB | |
| CXG97_RS25945 | fimA | −1.1275 | 0.041784 | type 1 fimbriae major subunit | |
| CXG97_RS13610 | – | −1.7529 | 0.002143 | flagella biosynthesis regulator Flk | |
| CXG97_RS25950 | – | −2.2246 | 0.00011843 | fimbrin fimI | |
| CXG97_RS09010 | – | 1.6293 | 0.049761 | fimbrial biogenesis outer membrane usher protein | |
| CXG97_RS09025 | – | 2.7839 | 2.36E−07 | fimbrial chaperone protein FimC | |
| fimbrial | CXG97_RS09015 | – | 1.7675 | 0.0015729 | fimbrial chaperone protein FimC |
| CXG97_RS17675 | – | 1.996 | 8.94E−05 | type 1 fimbrial protein | |
| CXG97_RS20510 | – | 1.2399 | 0.02421 | type 1 fimbrial protein | |
| CXG97_RS09020 | – | 2.3148 | 5.86E−06 | Fml fimbriae subunit | |
| flagellin | CXG97_RS11050 | – | 1.2589 | 0.039065 | flagellin FliC |
| LPS biosynthesis | CXG97_RS21640 | – | 2.4423 | 3.2651E−06 | ligase |
| CXG97_RS21660 | – | 1.9943 | 0.00014874 | LPS 1%2C2-glucosyltransferase | |
| CXG97_RS21655 | – | 2.0378 | 0.00015131 | LPS core heptose(II) kinase RfaY | |
| CXG97_RS21665 | – | 1.8557 | 0.00042876 | lipopolysaccharide 3-alpha-galactosyltransferase | |
| CXG97_RS06255 | – | −1.3255 | 0.017077 | lipid A biosynthesis lauroyl acyltransferase | |
| CXG97_RS21670 | – | 1.2497 | 0.019185 | lipopolysaccharide core heptose(I) kinase RfaP | |
| CXG97_RS21630 | – | −1.7497 | 0.038733 | ADP-heptose–LPS heptosyltransferase | |
| Proteins export and amino acid metabolism | |||||
| Protein export | CXG97_RS19815 | SecY | 2.0511 | 4.25E−05 | protein translocase subunit SecY |
| CXG97_RS23005 | tatC | 1.9541 | 0.00021961 | twin-arginine translocase subunit TatC | |
| CXG97_RS02115 | YajC | 1.7879 | 0.00069815 | preprotein translocase subunit YajC | |
| CXG97_RS22995 | TatA | 1.3288 | 0.012952 | twin-arginine translocase subunit TatA | |
| CXG97_RS23000 | TatB | 1.2944 | 0.014643 | twin-arginine translocase subunit TatB | |
| CXG97_RS02125 | SecF | 2.2484 | 0.020017 | protein translocase subunit SecF | |
| CXG97_RS21575 | SecB | 1.237 | 0.025291 | protein-export protein SecB | |
| CXG97_RS19155 | SecG | 1.1816 | 0.027567 | protein-export membrane protein SecG | |
| Arginine and proline metabolism | CXG97_RS23620 | argB | 3.3547 | 1.35E−05 | acetylglutamate kinase |
| CXG97_RS17080 | arcC | 1.6337 | 0.008478 | carbamate kinase | |
| CXG97_RS08705 | patD | 1.3149 | 0.037641 | gamma-aminobutyraldehyde dehydrogenase | |
| CXG97_RS25795 | argF | 8.588 | 1.37E−24 | ornithine carbamoyltransferase | |
| CXG97_RS03780 | speF | 1.5823 | 0.034956 | ornithine decarboxylase SpeF | |
| CXG97_RS06060 | putA | −3.5858 | 0.005959 | bifunctional proline dehydrogenase/L-glutamate gamma-semialdehyde dehydrogenase PutA | |
| CXG97_RS10130 | astB | −4.4096 | 0.006318 | succinylarginine dihydrolase | |
| CXG97_RS10135 | astD | −5.5193 | 0.000153 | N-succinylglutamate 5-semialdehyde dehydrogenase | |
| CXG97_RS17430 | speB | −1.8935 | 0.000611 | agmatinase | |
| CXG97_RS23160 | glnA | −1.458 | 0.009095 | glutamate–ammonia ligase | |