Fig. 5.

Sensitivity of OE-21 and KYSE-450 cells to multifraction proton irradiation with or without olaparib (3 μM). (A) OE-21 and (B) KYSE-450 cell survival after single or multifraction irradiation (8 Gy per four fractions) with or without prior treatment with olaparib for 1 h. The cells were fixed and stained with crystal violet and the number of colonies was counted in duplicate. Error bars correspond to the standard deviation of the mean. Data analysis was performed on pooled values from at least three independent experiments. Cont= control, Non-RT. = not irradiated and treated by drug only.