Table 3.
Radiographic parameters of the scoliosis in the 64 adults with scoliosis in the CHD cohort studied, comparing those with and without 22q11.2 deletion syndrome (22q11.2DS)
| Variables | 22q11.2DS with scoliosis (n=46) |
No 22q11.2DS with scoliosis (n=18) |
p Value |
|---|---|---|---|
| Major scoliosis curve type (total n=64) | |||
| Cervicothoracic | 0 (0%) | 1 (5.6%) | .2812 |
| Thoracic | 35 (76.1%) | 16 (88.9%) | .3200 |
| Thoracolumbar | 3 (6.5%) | 1 (5.6%) | 1.0000 |
| Lumbar | 8 (17.4%) | 0 (0%) | .0930 |
| Scoliosis surgery | 6 (13.0%) | 5 (27.8%) | .2667 |
| Subset with major thoracic scoliosis without surgery (n=41) | (n=30) | (n=11) | |
| Median degree of Cobb angle (IQR) | 21.3 (17–41) | 23.7 (20–28) | .9758 |
| Range | 11–111 | 13–40 | |
| Median number of vertebrae involved (IQR) | 6 (5–7) | 6 (6–8) | .3309 |
| Range | 4–9 | 4–8 | |
| Apex of curve (vertebra) | T6 (T4–T8) | T8 (T6–T9) | .0675 |
| Range | T3–T9 | T3–T10 | |
IQR, interquartile range; T, level of thoracic vertebra.