Table 3.
Amino acid transport systems identified in erythrocytes (Deves et al. 1992; Ellory et al. 1981; Ellory and Osotimehin 1984; Gardner and Levy 1972; López-Burillo et al. 1985; White 1985; Young et al. 1979)
System | Type of transport | Enhanced by | Inhibited by | Substrates |
---|---|---|---|---|
L | Facilitated diffusion | Cu+ | – | Leu, Ile, Val, Phe, Tyr, Gly, Cys, Ala |
y + L | Facilitated diffusion | – | – | Lys, Leu |
y+ | Facilitated diffusion | Na+ | Sucrose | Lys, Arg, Orn |
T | Facilitated diffusion | Cys | d-Trp, l-Phe, l-Try, Leu, 4-AzidoPhe, N-ethylmaleimide | L-Trp |
ASC | Secondary active transport | Na+ | Harmaline, cysteinyl-residue reagents | Ala, Ser, Cys, Gly, Gln |
Gly | Secondary active transport | Na+, Cl− | Bumetanide, furosemide | Gly, Sarcosine, pro |
N | Secondary active transport | Na+ | – | Gln, Asn, His |