Table 1.
Demographics, Clinical Characteristics, and Exposures for Participants With and Without Evidence of Acute Heartland Virus Infection
| HRTV-Infected | Noninfected | ||||
|---|---|---|---|---|---|
| n = 16 | n = 69 | ||||
| No. | (%) | No. | % | ||
| Demographics | |||||
| Male sex | 12 | (75) | 44 | (64) | |
| Age groups, y | |||||
| <40 | 0 | (0) | 24 | (35) | |
| 40–49 | 1 | (6) | 12 | (17) | |
| 50–59 | 2 | (13) | 11 | (16) | |
| 60–69 | 4 | (25) | 14 | (20) | |
| 70–79 | 8 | (50) | 7 | (10) | |
| ≥80 | 1 | (6) | 1 | (1) | |
| State of residence | |||||
| Missouri | 6 | (38) | 18 | (26) | |
| Arkansas | 2 | (13) | 4 | (6) | |
| Indiana | 2 | (13) | 1 | (1) | |
| Kentucky | 2 | (13) | 3 | (4) | |
| Oklahoma | 2 | (13) | 3 | (4) | |
| Kansas | 1 | (6) | 15 | (22) | |
| North Carolina | 1 | (6) | 2 | (3) | |
| Illinois | 0 | (0) | 4 | (6) | |
| Iowa | 0 | (0) | 3 | (4) | |
| Tennessee | 0 | (0) | 3 | (4) | |
| Othera | 0 | - | 12 | - | |
| Exposures | |||||
| Average number of hours outside per day | |||||
| <1 | 0 | (0) | 10 | (14) | |
| 1–4 | 6 | (38) | 28 | (41) | |
| 5–8 | 4 | (25) | 17 | (10) | |
| >8 | 6 | (38) | 13 | (19) | |
| Unknown | 0 | (0) | 1 | (1) | |
| Outdoor activities | |||||
| Yard work/gardening | 12 | (75) | 45 | (65) | |
| Walking | 5 | (42) | 37 | (54) | |
| Hunting | 3 | (25) | 14 | (20) | |
| Hiking/camping | 1 | (8) | 14 | (20) | |
| Vector exposure | |||||
| Attached tick | 13 | (81) | 34 | (49) | |
| Crawling tick | 10 | (63) | 33 | (48) | |
| Mosquito bite | 5 | (31) | 23 | (33) | |
| No known exposure | 2 | (13) | 13 | (20) | |
| Sandfly/midge bite | 1 | (6) | 3 | (4) | |
| Clinical characteristics | |||||
| Solicited | |||||
| Feverb | 16 | (100) | 69 | (100) | |
| Leukopeniab | 16 | (100) | 69 | (100) | |
| Thrombocytopeniab | 16 | (100) | 69 | (100) | |
| Fatigue | 15 | (94) | 69 | (100) | |
| Anorexia | 13 | (81) | 57 | (83) | |
| Nausea | 12 | (75) | 45 | (65) | |
| Headache | 11 | (69) | 58 | (84) | |
| Confusion | 11 | (69) | 26 | (38) | |
| Arthralgia | 10 | (63) | 39 | (57) | |
| Myalgia | 9 | (56) | 48 | (70) | |
| Diarrhea | 8 | (50) | 26 | (38) | |
| Cough | 5 | (31) | 23 | (33) | |
| Rash | 2 | (13) | 24 | (35) | |
| Easy bruising | 1 | (6) | 14 | (20) | |
| Unsolicitedc | |||||
| Chills | 3 | (19) | 27 | (39) | |
| Gait disturbance | 3 | (19) | 2 | (3) | |
| Dizziness | 2 | (13) | 0 | (0) | |
| Vomiting | 2 | (13) | 4 | (6) | |
| Altered/lost taste | 2 | (13) | 0 | (0) | |
aOther includes 1 individual each for Colorado, Florida, Georgia, Louisiana, Massachusetts, Nebraska, North Dakota, Ohio, Texas, Virginia, and West Virginia; percentage not calculated but would be 1% for each of the 12 states.
bRequired signs and symptoms for testing.
cOnly symptoms reported by >1 individual with acute Heartland virus infection are listed.