Table 3.
Genotype and allele frequencies of −794 CATT5‐8 MIF polymorphism in CS and BC
| Polymorphism‐794 CATT5‐8 | CS n = 182 (%) | BC n = 114 (%) | OR | CI 95% | P* value |
|---|---|---|---|---|---|
| Genotype | |||||
| 5,5 | 3 (1) | 7 (6) | 4.1 | 0.84‐26.04 | .04 |
| 5,6 | 55 (32) | 37 (32) | 1.18 | 0.60‐2.30 | .59 |
| 5,7 | 12 (7) | 0 | – | – | – |
| 6,6a | 51 (28) | 29 (25) | 1 | ||
| 6,7 | 49 (25) | 27 (24) | 0.96 | 0.47‐1.96 | .92 |
| 7,7 | 12 (7) | 14 (12) | 2.0 | 0.76‐5.54 | .11 |
| Allele | |||||
| 5 | 73 (21) | 51 (22) | 1.17 | 0.75‐1.83 | .44 |
| 6a | 206 (57) | 122 (54) | 1 | ||
| 7 | 85 (22) | 55 (24) | 1.09 | 0.71‐1.67 | .67 |
| Genetic model (Do) | |||||
| ‐, ‐a | 109 (62) | 73 (64) | 1 | ||
| ‐, 7 + 7,7 | 73 (38) | 41 (36) | 0.83 | 0.50‐1.39 | .47 |
Abbreviations: Do, dominant inheritance genetic model; ‐,‐, Genotypes without the risk allele; BC, breast cancer; CS, control subjects; OR, odds ratio; CI, confidence interval; P* value = X2 test.
a
Reference category.