Table 2.
Diet and intervention from the beginning to the end of the study.
| Markers | HFD | STZ injection | Normal diet | Saline gavage | Probiotic gavage | Prebiotic intake | Prebiotic and prebiotic intake |
|---|---|---|---|---|---|---|---|
| HC | — | — | Weeks 1 to 13 | — | — | — | — |
| DC | Weeks 2 to 5 | End of the week 5 | Weeks 6 to 13 | — | — | — | — |
| DSh | Weeks 2 to 5 | End of the week 5 | Weeks 6 to 13 | Weeks 6 to 13 | — | — | — |
| DL | Weeks 2 to 5 | End of the week 5 | Weeks 6 to 13 | — | Weeks 6 to 13 | — | — |
| DI | Weeks 2 to 5 | End of the week 5 | Weeks 6 to 13 | — | — | Weeks 6 to 13 | — |
| DLI | Weeks 2 to 5 | End of the week 5 | Weeks 6 to 13 | — | — | — | Weeks 6 to 13 |
HC: healthy control; DC: diabetic control; DSh: diabetic sham; DL: diabetics treated by L. plantarum; DI: diabetics treated by inulin; DLI: diabetics treated by L. plantarum and inulin; T2DM: type 2 diabetes mellitus; BDNF: brain-derived neurotrophic factor; HFD: high-fat diet; STZ: streptozotocin.