Table 1.
The genes that regulated by Nrf2.
| Gene name | Control | AA30 | DOX | DOX+AA30 |
|---|---|---|---|---|
| Cat | 0.88 ± 0.12 | 0.93 ± 0.09 | 0.32 ± 0.07∗ | 0.73 ± 0.05# |
| Sod1 | 2.16 ± 0.22 | 2.15 ± 0.34 | 0.64 ± 0.12∗ | 1.89 ± 0.18# |
| Sod2 | 3.17 ± 0.23 | 4.76 ± 0.21∗ | 1.14 ± 0.11∗ | 2.67 ± 0.24# |
| Gpx1 | 0.94 ± 0.09 | 0.89 ± 0.07 | 0.45 ± 0.04∗ | 0.78 ± 0.08# |
| Gpx4 | 3.58 ± 0.22 | 4.54 ± 0.13∗ | 2.14 ± 0.34∗ | 3.13 ± 0.46# |
| HO-1 | 0.25 ± 0.04 | 0.27 ± 0.05 | 0.09 ± 0.01∗ | 0.18 ± 0.02# |
| NQO1 | 0.58 ± 0.03 | 0.55 ± 0.05 | 0.32 ± 0.04∗ | 0.43 ± 0.05# |
| Gsta3 | 0.09 ± 0.01 | 0.08 ± 0.02 | 0.04 ± 0.01∗ | 0.07 ± 0.01# |
| Gsta4 | 2.44 ± 0.21 | 2.54 ± 0.43 | 1.02 ± 0.11∗ | 2.54 ± 0.12# |
∗ P < 0.05 vs. control group; #P < 0.05 vs. DOX group.