Table 8.

STRING Protein Interactants and Their Functions for NIPA2.

GENE	Description
NIPA2	Magnesium transporter NIPA2; Acts as a selective Mg(2+) transporter; Belongs to the NIPA family.
ACVR1C	Activin receptor type-1C; Serine/threonine protein kinase which forms a receptor complex on ligand binding.
SMAD2	Mothers against decapentaplegic homolog 2; also known as SMAD family member 2; Receptor-regulated SMAD (R-SMAD) that is an intracellular signal transducer and transcriptional modulator activated by TGF-beta (transforming growth factor) and activin type 1 receptor kinases.
ACVR1	Activin receptor type 1; On ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases.
BMP6	Bone morphogenetic protein 6; Induces cartilage and bone formation; Bone morphogenetic proteins.
UXS1	UDP-glucuronic acid decarboxylase 1; Catalyzes the NAD-dependent decarboxylation of UDP- glucuronic acid to UDP-xylose. Necessary for the biosynthesis of the core tetrasaccharide in glycosaminoglycan biosynthesis.
SMAD3	Mothers against decapentaplegic homolog 3; also known as SMAD family member 3; Receptor-regulated SMAD (R-SMAD) that is an intracellular signal transducer and transcriptional modulator activated by TGF-beta (transforming growth factor) and activin type 1 receptor kinases.
SMAD4	Mothers against decapentaplegic homolog 4; also known as SMAD family member 4; In muscle physiology, plays a central role in the balance between atrophy and hypertrophy.
CHUK	Inhibitor of nuclear factor kappa-B kinase subunit alpha; Serine kinase that plays an essential role in the NF- kappa-B signaling pathway.
BMP5	Bone morphogenetic protein 5; Induces cartilage and bone formation; Bone morphogenetic proteins.
BMPR1A	Bone morphogenetic protein receptor type-1A; On ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases.
BMPR2	Bone morphogenetic protein receptor type- 2; On ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases.
TGFBR1	TGF-beta receptor type-1; Transmembrane serine/threonine kinase forming with the TGF-beta type II serine/threonine kinase receptor. Regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, and immunosuppression.
SMAD9	Mothers against decapentaplegic homolog 9; also known as SMAD family member 9; Transcriptional modulator activated by BMP (bone morphogenetic proteins) type 1 receptor kinase.
BMP7	Bone morphogenetic protein 7; Induces cartilage and bone formation. May be the osteoinductive factor responsible for the phenomenon of epithelial osteogenesis. Plays a role in calcium regulation and bone homeostasis; Bone morphogenetic proteins.
BMPR1B	Bone morphogenetic protein receptor type-1B; On ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases.
SMAD1	Mothers against decapentaplegic homolog 1; also known as SMAD family member 1; Transcriptional modulator activated by BMP (bone morphogenetic proteins) type 1 receptor kinase.
SMAD5	Mothers against decapentaplegic homolog 5; also known as SMAD family member 5; Transcriptional modulator activated by BMP (bone morphogenetic proteins) type 1 receptor kinase. SMAD5 is a receptor-regulated SMAD (R-SMAD).
ACVR1B	Activin receptor type-1B; Transmembrane serine/threonine kinase activin type-1 receptor forming an activin receptor complex with activin receptor type-2 (ACVR2A or ACVR2B). Transduces the activin signal from the cell surface to the cytoplasm and is thus regulating many physiological and pathological processes including neuronal differentiation and neuronal survival, hair follicle development and cycling.

Source: STRING.org.