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. 2020 May 6;21(9):3296. doi: 10.3390/ijms21093296

Table 16.

Summary of Associated Neurodevelopmental Maladies Across All Four Genes.

Number Neurodevelopmental Disorders/Diseases NIPA1 NIPA2 CYFIP1 TUBGCP5
1 Prader–Willi Syndrome YES YES YES YES
2 Angelman Syndrome YES YES YES NO
3 15q11.2 Deletion Syndrome with Attention Deficit Hyperactive Disorder & Learning Disability YES YES YES NO
4 Autism Spectrum Disorder YES YES YES YES
5 Schizophrenia YES YES YES YES
6 Epilepsy YES YES YES YES
7 Down Syndrome YES YES YES YES
8 Microcephaly YES YES NO YES
9 Developmental Disorder NO NO YES NO
10 Peripheral Nervous System Disease YES NO NO NO

Source: GeneCards.org, MalaCards.org, SAFARI.Org, KEGG, PubMed, Gene Ontology (GO), OMIM.org, Entrez. and UniProtKB/Swiss-Prot.