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. 2020 Apr 26;21(9):3055. doi: 10.3390/ijms21093055

Table 7.

Drosophila model of a neurodegenerative brain tumor.

Brain Tumor
Drosophila Model Developmental Stage Assay Used for Neuropathology References
Drosophila orthologs of human genes
bratchs mutant, bratchs; pcna–GFP and bratchs; CG15864MB04166 double mutants Adult Histological staining for vacuole quantification, climbing assay, immunostaining with anti–cleaved Dcp–1 for prevalence of apoptosis [166]