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. 2020 Apr 30;21(9):3199. doi: 10.3390/ijms21093199
SOST gene encoding sclerostin
Wnt Wingless-related integration site
Fz Frizzled
LRP5/6 Low-density Lipoprotein Receptor-related Protein 5/6
TCF T-cell factor
LEF Lymphoid Enhancer-binding factor
PPARγ Peroxisome Proliferator-Activated Receptor γ
C/EBPα CCAAT/Enhancer-Binding Protein α
Runx2 Runt-related transcription factor 2
OPG Osteoprotegerin
RANKL Receptor Activator of Nuclear Factor Kappa-Β ligand
PTH Parathyroid hormone
LRP4 Low-density Lipoprotein Receptor-related Protein 4
P1NP Procollagen type 1 N-terminal Propeptide
BsAP Bone-specific Alkaline Phosphatase
SIBLINGS Small Integrin Binding Ligand N-Glycoproteins
MEPE Matrix Extracellular Phosphoglycoprotein
ASARM Acidic Serine Aspartate-Rich MEPE-associated motif
PHEX Phosphate-regulating neutral Endopeptidase, X-linked
KO Knockout
WT Wild type
Bax Bcl2- associated X protein
DMP1 Dentin matrix acidic phosphoprotein 1
CKD Chronic kidney disease
VSMC Vascular smooth muscle cell
sFRP secreted Frizzled-related protein
ESRD End-stage renal disease
Jck Juvenile cystic kidney
FGF23 Fibroblast growth factor 23
MGP Matrix γ-carboxyglutamic acid
AVC Aortic valve calcification
DKK3 Dickkopf-related protein 3
DKK1 Dickkopf-related protein 1