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Sigmoidal curves of the effect of the compounds 3 (blue) and 4 (ind, orange) on the release of nitrites in RAW 264.7 macrophage murine cells. Clearly, the curves corresponding to metal-complex compound (3, EC50NO = 28.76 ± 4.23 μg/mL) are below to the ligand one (4, EC50NO = 35.92 ± 0.97 μg/mL). The data represent the mean ± S.D. of at least two independent experiments performed in triplicate.
