Table 1.
Clinical characteristics of chronic thromboembolic pulmonary hypertension (CTEPH) patients.
| Parameter | Mean ± SD or % | Cohort (n) * | |
|---|---|---|---|
| Age at diagnosis (years) | 61 | ± 13 | 40 |
| Women (%) | 53 | 40 | |
| 6-minute walking distance (m) | 425 | ± 86 | 34 |
| Previous history of pulmonary embolisms (%) | 87 | 39 | |
| Family history of thrombosis or pulmonary embolisms (%) | 11 | 36 | |
| Presence of myeloproliferative disease (%) | 7.5 | 40 | |
| N-terminal pro-brain natriuretic peptide (ng/l) | 1893 | ± 4186 | 36 |
| WHO functional class [26] | 36 | ||
| WHO functional class II (%) | 42 | ||
| WHO functional class III (%) | 58 | ||
| Treatment | 39 | ||
| Pulmonary endarterectomy (%) | 33 | ||
| Pulmonary endarterectomy + medication (%) | 23 | ||
| Balloon pulmonary angioplasty + medication (%) | 10 | ||
| Pulmonary endarterectomy + balloon pulmonary angioplasty + medication (%) | 3 | ||
| Medication only (%) | 31 | ||
| Haemodynamics | |||
| Mean pulmonary artery pressure (mmHg) | 44 | ± 13 | 36 |
| Pulmonary artery wedge pressure (mmHg) | 9 | ± 5 | 34 |
| Pulmonary vascular resistance (Wood Units) | 7.9 | ± 3.6 | 35 |
| Cardiac output (L/min) | 4.7 | ± 1.1 | 28 |
| Cardiac index (L/min/m2) | 2.5 | ± 0.5 | 27 |
* n varies for each parameter. Exact numbers are listed in this column; Abbreviations: SD: standard deviation, WHO: World Health Organization.