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. 2020 Apr 25;21(9):3040. doi: 10.3390/ijms21093040

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© 2020 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

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Differentially expressed protein-coding genes between HCM patients and normal controls. (A) Volcano plot of the differentially expressed genes (DEGs). The x-axes show the log2 transformed fold change, and the y-axes show the log10 transformed false discovery rate (FDR). Red dots are DEGs with an FDR < 0.05 and fold change > 1.5. (B–D) Dot plots of the expression levels of ANKRD1, TGFB3, and FHL2 in normal controls (NC) and HCM patients, ***FDR < 0.001. (E) Bar plots of the significantly enriched cardiovascular-related Gene Ontology (GO) terms for the differentially expressed protein-coding genes.