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. 2020 May 4;21(9):3253. doi: 10.3390/ijms21093253
miRNA microRNA
siRNA small interfering RNA
mRNA messenger RNA
LNA locked nucleic acid
AGO Argonaute protein
RISC RNA-induced silencing complex
NV nanovector
NP nanoparticle
PEG polyethylene glycol
PLGA poly(lactic-co-glycolic acid)
EV extracellular vesicles
FDA Food and drug administration of Unites States
EMA European medicine agency
PA pulmonary artery
PH pulmonary hypertension
PAH pulmonary artery hypertension
UTR untranslated region
PAEC pulmonary artery endothelial cell
HPAEC human pulmonary artery endothelial cell
PASMC pulmonary artery smooth muscle cell
HPASMC human pulmonary artery smooth muscle cell
PAF pulmonary artery fibroblast
HIF-1 α hypoxia inducible factor 1-alpha
BMPR2 bone morphogenetic protein receptor type II
mTOR mammalian target of rapamycin
PTPB1 polypyrimidine tract-binding protein 1
PKM1/M2 pyruvate kinase isozymes M1/M2
SMAD3 mothers against decapentaplegic homolog 3
TGFBR2 transforming growth factor beta receptor 2
α-SMA Alpha-smooth muscle actin
SMAD2/7 mothers against decapentaplegic homolog 2/7
MICAL2 microtubule associated monooxygenase, calponin and LIM domain containing 2
ERK1/2 extracellular signal-regulated kinase ½
FHL-1 four and a half LIM domain protein
CCNL2 cyclin-L2
LMOD1 leiomodin 1
MEF2C myocyte-specific enhancer factor 2C
PTEN phosphatase and tensin homolog
FGF fibroblast growth factor
MYC master regulator of cell entry and proliferative metabolism
HDAC4 histone deacetylase 4
CDK6 cell division protein kinase 6