| MDS | myelodysplastic syndrome |
| BDH2 | type 2-hydroxybutyrate dehydrogenase |
| BM | bone marrow |
| qRT-PCR | quantitative real-time polymerase chain reaction |
| BDH2-KD | BDH2 knockdown |
| AML | acute myeloid leukemia |
| RUNX1 | runt-related transcription factor 1 |
| c-CBL | c-Casitas B-lineage lymphoma |
| DNMT3A | DNA methyltransferase 3 alpha |
| TET2 | tet methylcytosine dioxygenase 2 |
| EZH2 | enhancer of zeste homolog 2 |
| U2AF1 | U2 small nuclear RNA auxiliary factor 1 |
| U2AF35 | U2 small nuclear RNA auxiliary factor 35 |
| ZRSR2 | zinc finger CCCH type, RNA binding motif, and serine/arginine-rich 2 |
| SRSF2 | serine and arginine-rich splicing factor 2 |
| SF3B | splicing factor 3b subunit 1 |
| GDF11 | growth differentiation factor-11 |
| GDF15 | growth differentiation factor-15 |
| LFS | Leukemia-free survival |
| OS | overall survival |
| LCN2 | lipocalin 24p3 |
| 2,5-DHBA | 2,5-dihydroxybenzoic acid |
| WHO | World Health Organization |
| IPSS-R | Revised International Prognostic Scoring System |
| RA | refractory anemia |
| RARS | refractory anemia with ring sideroblast |
| RAEB1 | refractory anemia with excess of blast 1 |
| RAEB2 | refractory anemia with excess of blast 2 |
| MDS/MPN | myelodysplasitic syndrome/myeloproliferative neoplasm |
| NNT | nicotinamide nucleotide transhydrogenase |
| TCA | tricarboxylic acid |
| SLC25A1 | solute carrier 25 A1 |
| BBF2H7/CREB3L2 | CAMP responsive element binding protein 3 like 2 |
| ER | endoplasmic reticulum |
| TGF-β | transforming growth factor-β |
| MMP-9 | Matrix metalloproteinase-9 |
| PIK3CD | Phosphoinositide-3-kinase, catalytic, delta polypeptide |
| TNFSF13B | tumor necrosis factor superfamily member 13B |
| IL | interleukin |
| CCL | Chemokine ligand |
| PRL | prolactin |