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. 2020 Apr 29;17(9):3089. doi: 10.3390/ijerph17093089

Table 3.

Most cited papers.

No Title Total Citation Published Year Cite Rate
1 The body-mass index, airflow obstruction, dyspnea, and exercise capacity index in chronic obstructive pulmonary disease 2046 2004 136.4
2 A 4-year trial of tiotropium in chronic obstructive pulmonary disease 1390 2008 126.4
3 Susceptibility to Exacerbation in Chronic Obstructive Pulmonary Disease. 1298 2010 144.2
4 Effect of exacerbation on quality of life in patients with chronic obstructive pulmonary disease 1223 1998 58.2
5 Randomised, double blind, placebo-controlled study of fluticasone propionate in patients with moderate to severe chronic obstructive pulmonary disease: the ISOLDE trial* 964 2000 50.7
6 Development and first validation of the COPD Assessment Test 933 2009 93.3
7 Severe acute exacerbations and mortality in patients with chronic obstructive pulmonary disease 868 2005 62.0
8 Outcomes following acute exacerbation of severe chronic obstructive lung disease 863 1996 37.5
9 Combined salmeterol and fluticasone in the treatment of chronic obstructive pulmonary disease: a randomised controlled trial 749 2003 46.8
10 Chronic obstructive pulmonary disease: current burden and future projections 698 2006 53.7
11 Time course and recovery of exacerbations in patients with chronic obstructive pulmonary disease 655 2000 34.5
12 A long-term evaluation of once-daily inhaled tiotropium in chronic obstructive pulmonary disease 609 2002 35.8
13 Azithromycin for Prevention of Exacerbations of COPD 578 2011 72.3
14 Reduction of hospital utilization in patients with chronic obstructive pulmonary disease—A disease-specific self-management intervention 576 2003 36.0
15 Effects of pulmonary rehabilitation on physiological and psychosocial outcomes in patients with chronic obstructive pulmonary disease 568 1995 23.7
16 Efficacy and safety of budesonide/formoterol in the management of chronic obstructive pulmonary disease 550 2003 34.4
17 Results at 1 year of outpatient multidisciplinary pulmonary rehabilitation: a randomised controlled trial 536 2000 28.2
18 Dyspnea is a better predictor of 5-year survival than airway obstruction in patients with COPD 500 2002 29.4
19 Improved health outcomes in patients with COPD during 1 year’s treatment with tiotropium 492 2002 28.9
20 Maintenance therapy with budesonide and formoterol in chronic obstructive pulmonary disease 472 2003 29.5
21 Global Strategy for the Diagnosis, Management, and Prevention of Chronic Obstructive Lung Disease 2017 Report 467 2017 233.5
22 Relation of sputum inflammatory markers to symptoms and lung function changes in COPD exacerbations 458 2000 24.1
23 Tiotropium in combination with placebo, salmeterol, or fluticasone-salmeterol for treatment of chronic obstructive pulmonary disease—A randomized trial 448 2007 37.3
24 Meta-analysis of respiratory rehabilitation in chronic obstructive pulmonary disease 443 1996 19.3
25 Risk factors of readmission to hospital for a COPD exacerbation: a prospective study 421 2003 26.3
26 Mortality after hospitalization for COPD 380 2002 22.4
27 Depressive symptoms and chronic obstructive pulmonary disease—Effect on mortality, hospital readmission, symptom burden, functional status, and quality of life 369 2007 30.8
28 How well do we care for patients with end stage chronic obstructive pulmonary disease (COPD)? A comparison of palliative care and quality of life in COPD and lung cancer 338 2000 17.8
29 Randomized controlled trial of respiratory rehabilitation 337 1994 13.5
30 Early therapy improves of chronic obstructive outcomes of exacerbations pulmonary disease 335 2004 22.3
31 Quality of life changes in COPD patients treated with salmeterol 331 1997 15.0
32 Prevalence of COPD in Spain: impact of undiagnosed COPD on quality of life and daily life activities 323 2009 32.3
33 A 6-month, placebo-controlled study comparing lung function and health status changes in COPD patients treated with tiotropium or salmeterol 323 2002 19.0
34 Health outcomes following treatment for six months with once daily tiotropium compared with twice daily salmeterol in patients with COPD 317 2003 19.8
35 Roflumilast—an oral anti-inflammatory treatment for chronic obstructive pulmonary disease: a randomised controlled trial 315 2005 22.5
36 Analysis of the factors related to mortality in chronic obstructive pulmonary disease—Role of exercise capacity and health status 314 2003 19.6
37 Interpreting thresholds for a clinically significant change in health status in asthma and COPD 313 2002 18.4
38 Short- and long-term effects of outpatient rehabilitation in patients with chronic obstructive pulmonary disease: A randomized trial 308 2000 16.2
39 Effect of exacerbations on quality of life in patients with chronic obstructive pulmonary disease: a 2 year follow up study 299 2004 19.9
40 Phosphodiesterase-4 inhibitors for asthma and chronic obstructive pulmonary disease 298 2005 21.3

Note: * The inhaled steroids in obstructive lung disease in Europe (ISOLDE).