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Domain structure and functional regions of the LUBAC subunits, HOIL-1L, HOIP, and SHARPIN. LTM, LUBAC-tethering motif; UBL, ubiquitin-like; NZF, Npl4-type zinc finger; RING, really interesting new gene; IBR, in-between RING; PUB, PNGase/UBA or UBX; ZF, zinc finger; UBA, ubiquitin-associated; LDD, linear ubiquitin chain determining domain; PH, Pleckstrin-homology.
