Table 1.
Demographic and laboratory findings of patients
IPF (n=50) | Non-IPF (n=42) | p value | |
Age (Mean±SD) | 67.4±7.1 | 64.9±7.2 | 0.08 |
Gender (n) (Female/Male) | 12/38 | 13/29 | |
Non-smoker (n) Smoker Ex-smoker |
16 10 23 |
15 6 20 |
0.76 |
BMI | 27.3±3.9 | 29±4.1 | 0.04 |
6DYT = 6MWT(mt) | 342.8±93 | 362.787.8 | 0.30 |
FEV1% | 69.6±14.4 | 77.8±17.7 | 0.01 |
FVC % | 63±15.2 | 71.6±15.9 | 0.01 |
TLCO % | 42.2±15 | 53.2±20.9 | 0.006 |
Clubbing, n | 15 | 3 | 0.015 |
Symptom *, n(%) Dispnea Coughing Sputum |
46 (92%) 28 (56%) 10 (20%) |
33 (78,6%) 21 (50%) 16 (38%) |
0,123 0,71 0,09 |
Comorbidity* (n) Total (+/-) Hypertension Diabetes Coronary Artery Disease COPD Others |
32/18 12 16 18 5 2 |
32/10 16 16 8 5 3 |
0.51 |
Radiological findings* (n) Traction bronchiectasis Honeycomb Fibrosis Glossy opacity Emphysema |
23 41 44 28 13 |
8 18 35 35 10 |
0.006 <0.001 0.72 0.005 0.82 |
Sedimentation | 26 (8,100) | 26 (4,119) | 0.74 |
CRP | 0.6 (0.1 , 25) | 0.6 (0.1,13.5) | 0.36 |
*= more than one finding in a patient
Abbrevations: IPF:Idiopatic Pulmonary Fibrosis; BMI: Body mass index; 6MWT: Six minute walk test
SF-36 = Short form-36 Quality of Life; HAM-A = Hamilton Anxiety score; HAM-D = Hamilton Depression score; GAP = Gender Age Physiologic index; 6MWT = 6 Minute walk Test