Table 1.
Baseline characteristics at the time of IPF diagnosis
| Characteristics | |
| Subjects | 107 |
| Male | 82 |
| Age (yrs) | 66.9±7.1 |
| Smoking history | |
| Never smoke | 25 |
| Current smoker | 3 |
| Ex-smoker | 69 |
| Pack-year | 40.2±25.5 |
| Surgical lung biopsy (Yes) | 107 |
| Familial interstitial lung diseases (Yes) | 16 |
| Blood tests (n=107) | |
| KL-6 (U/mL) | 1147±826 |
| SP-D (ng/mL) | 219±139 |
| LDH (U/L) | 225±43 |
| CRP (mg/dL) | 0.40±1.81 |
| PaO2 (Torr) | 84.9±8.3 |
| Pulmonary function (n=107) | |
| FVC (L) | 2.82±0.79 |
| FVC %pred (%) | 85.3±17.0 |
| FEV1/FVC (%) | 79.0±6.5 |
| DLco %pred (%) | 82.1±19.3 |
| DLco (mL/min/mm Hg) | 14.8±3.9 |
| 6-minute walk test (n=95) | |
| Distance (meter) | 458±82 |
| Minimum SpO2 (%) | 91±4 |
| Bronchoalveolar lavage fluid findings (n=81) | |
| Total cell count (×10^5) | 2.07±1.55 |
| Macrophages (%) | 78.2±18.0 |
| Lymphocytes (%) | 16.9±16.8 |
| Neutrophils (%) | 3.4±5.0 |
| Eosinophils (%) | 1.6±1.9 |
Data are presented as n or mean±standard deviation. Definition of abbreviations: IPF: idiopathic pulmonary fibrosis, KL-6: Krebs von den Lungen-6, SP-D: surfactant protein-D, LDH: lactate dehydrogenase, CRP: C-reactive protein, PaO2: partial pressure of oxygen in arterial blood, FVC: forced vital capacity, %pred: % predicted, FEV1: forced expiratory volume in 1 second, DLco: diffusion capacity of the lung for carbon monoxide, SpO2: arterial oxygen saturation measured by pulse oximetry.