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. 2020 May 24;19:190. doi: 10.1186/s12936-020-03263-z

Table 4.

Genetic analysis of Pfdhfr and Pfdhps SNPs in Plasmodium falciparum isolates collected from pregnant women at Msambweni County Referral Hospital in Kwale County, Kenya

SNP (N = 106) Mutant type n (%, 95% CI) Mixed type n (%, 95% CI) Wild type n (%, 95% CI)
a Prevalence of Pfdhfr and Pfdhps SNPs in isolated P. falciparum malaria parasites
 51 94 (88.68, 80.69 to 93.76) 6 (5.66, 2.32 to 12.41) 5 (4.72, 1.75 to 11.19)
 59 83 (78.30, 69.03 to 85.48) 21 (19.81, 12.95 to 28.91) 2 (1.89, 0.33 to 7.32)
 108 99 (93.40, 86.40 to 97.08) 6 (5.66, 2.32 to 12.41) 0 (0.00)
 437 100 (94.34, 87.59 to 97.68) 4 (3.77, 1.21 to 9.94) 2 (1.89, 0.33 to 7.32)
 540 97 (91.51, 84.07 to 95.80) 1 (0.64, 0.05 to 5.90) 5 (4.72, 1.75 to 11.19)
Genotype Mutants only Mutants + Mixed
N % N %
b Different combinations of PfDHFR/PfDHPS haplotype mutations
 Dup 7 6.6 0 0
 Tri 7 6.6 4 3.8
 Quad 22 20.8 11 10.4
 Quint 70 66 91 85.8