Table 3.

Antigenicity of monomeric and assembled Δ123 and Δ123A7 and cell culture-derived Δ123-HMW measured by direct ELISA

Numbers show the fraction of antibody reactivity compared with that of monomeric Δ123, which was assigned a reactivity of 1.0 for all antibodies. Indicated are relative binding of < 0.5 (yellow shading), < 0.1 (red shading), and > 2.0 (green shading).

^a L, linear; DC, discontinuous.

^b Neutralizing activity.

^c Epitope domain targeted (reference). NK, not known. For consistency, the Ser512-Trp529 domain is referred to as AS512.

^d Δ123A7 monomer.