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. 2020 May 1;21(9):3210. doi: 10.3390/ijms21093210

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© 2020 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

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Unaltered infarct size and cardiac function in PLD2-deficient mice 24 h after I/R. (A) Determination of infarct size and area at risk (AAR) as percentage of the left ventricle (LV), and infarct size (INF) as percentage of the area at risk showed no differences as analyzed by TTC staining 24 h after I/R in Pld2^+/+ vs. Pld2^-/^- mice, n = 7–9. (B–E) Echocardiographic analysis (baseline versus 24 h after I/R) of (B) ejection fraction, (C) cardiac output, (D) fractional shortening and (E) stroke volume, n = 6. Bar graphs depict mean values ± SEM. Statistical analysis was performed using the two-tailed Student’s t-test. AMI = acute myocardial infarction.