| ALT | alternative lengthening of telomeres |
| aFAP | attenuated familial adenomatous polyposis |
| CC | colon cancer |
| CCE | colon capsule endoscopy |
| CCL20 | C-chemokine cysteine motif chemokine ligand 20 |
| cfDNA | cell-free DNA |
| CGH | comparative genomic hybridization |
| CIMP | CpG island methylator phenotype |
| CIN | chromosomal instability |
| CRC | colorectal cancer |
| CTCs | circulating tumor cells |
| CT | computed tomographic |
| ctDNA | circulating tumor DNA |
| EpCAM | epithelial cell adhesion molecule |
| FAP | familial adenomatous polyposis |
| FDA | Food and Drug Administration |
| FFPE | formalin-fixed paraffin-embedded |
| FIT | fecal immunochemical test |
| FOBT | fecal occult blood test |
| gFOBT | guaiac fecal occult blood test |
| Hb | hemoglobin |
| HNPCC | hereditary non-polyposis colorectal cancer |
| HPs | hyperplastic polyps |
| JPS | Juvenile polyposis syndrome |
| LOH | loss of heterozygosity |
| LS | Lynch syndrome |
| MAP | MUTYH-associated polyposis |
| MMR | mismatch repair pathway |
| mt-sDNA | multitarget stool DNA |
| ncRNA | non-coding RNA |
| NER | nucleotide excision repair genes |
| NGS | next-generation sequencing |
| NPV | negative predictive value |
| PHTS | hamartoma tumors syndrome |
| PJS | Peutz-Jeghers syndrome |
| PPAP | Polymerase proofreading-associated polyposis |
| PPV | positive predictive value |
| RC | rectal cancer |
| RLT | relative telomere length |
| SSA/Ps | sessile serrated polyps |
| UK | United Kingdom |
| USA | United States of America |
| WNT | Wingless/Int-1 pathway |