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. 2020 May 2;21(9):3219. doi: 10.3390/ijms21093219
BBB blood–brain barrier
CNS central nervous system
EAE experimental autoimmune encephalomyelitis
IL-1β interleukin 1β
IL-6 interleukin 6
TNFα tumor necrosis factor
CX3CL1 chemokine (C-X3- C motif) ligand 1or fractalkine
CX3CR1 chemokine (C-X3-C motif) receptor 1
MCP-1 monocyte chemoattractant protein 1
CCL2 chemokine (C-C motif) ligand 2
MIP-1α macrophage inflammatory protein 1-alpha
CCL3 chemokine (C-C motif) ligand 3
RANTES regulated on activation, normal T cell expressed and secreted
CCL5 chemokine (C-C motif) ligand 5
TREM2 triggering receptor expressed on myeloid cells 2
LPS lipopolysaccharide
ApoE apolipoprotein E
MERTK Mer receptor tyrosine kinase
MEGF10 multiple EGF-like-domains 10
BAI1 brain-specific angiogenesis inhibitor 1
GFAP glial fibrillary acidic protein
EGF epidermal growth factor
FGF fibroblast growth factor
TGF-β transforming growth factor β
ER estrogen receptors
PR progesterone receptor
AR androgen receptor
PTMs post-translational modifications
NF-κB nuclear factor kappa-light-chain-enhancer of activated B cells
MMP9 metalloproteinase 9
PGE2 prostaglandin E2
iNOS nitric oxide synthases
SERMs selective estrogen receptor modulators
STEAR selective tissue estrogenic activity regulator