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. 2020 May 4;21(9):3246. doi: 10.3390/ijms21093246

Figure 1.

Figure 1

Classification and domain structure of the histone deacetylases (HDACs). The colored boxes on the domain structure are indicated as follows: orange, zinc-dependent HDAC domain; mint, NAD+-dependent SIRT domain; purple, MEF2 binding domain; yellow, nuclear localization signal; blue, nuclear export signal; and peach, zinc finger binding domain. HDAC, histone deacetylase, SIRT, sirtuin; and MEF2, myocyte enhancer factor 2.