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. 2020 May 7;21(9):3312. doi: 10.3390/ijms21093312

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© 2020 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

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The expression levels of pain receptors and involved molecules in the cerebellum lobule VII. The immunoblotting images contain five lanes of protein in following order: control, CFA, CFA + EA, CFA + SHAM, and CFA + KO groups. There are significant decreases of (A) TRPV1, (B) Nav1.7, (C) Nav1.8, (D) ASIC3, (E) pmTOR, (F) pPI3K, (G) pAkt, (H) pERK, (I) RAGE, (J) pPKCε, (K) pPKAIIα, (L) pNFκB, (M) pCREB and, (N) S100B protein level in CFA + EA and CFA + KO groups compared to CFA and CFA + SHAM groups (* p < 0.05).