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. 2020 May 7;21(9):3316. doi: 10.3390/ijms21093316
nE2 estradiol synthesized in the nervous system
ERs estrogen receptors
ERα estrogen receptors isoform α
ERβ estrogen receptors isoform β
GPCRs G-protein-coupled receptors
GPER-1 estrogen-G-protein-coupled receptors-1
Gαq-mER Gαq-membrane estrogen receptor
ER-X estrogen receptor-X
GABA Gamma aminobutyric acid
VOR vestibulo-ocular reflex
PCs Purkinje cells
BDNF brain-derived neurotrophic factor; mGluR1a: metabotropic glutamate receptors type 1a
PF-LTP long term potentiation at the parallel fiber-Purkinje cell synapse
PF-LTD long term depression at the parallel fiber-Purkinje cell synapse
LTZ letrozole
ICI 182,780 estrogen receptor antagonist
NMDAR N-methyl-D-aspartate receptor
LTP long term potentiation
LTD long term depression