Table 1.
Summary of findings indicating aromatase and estrogen receptors expression and distribution within the cerebellar cortex in rodents.
| Cerebellar Cortex Layer | Aromatase | ERα | ERβ | GPER-1 | ||||
|---|---|---|---|---|---|---|---|---|
| Childhood | Adult | Childhood | Adult | Childhood | Adult | Childhood | Adult | |
| Gc | 1, 7 | 1 | 11, 12, 20 | 8, 11, 14, 15, 19, 21 | 18 | |||
| PC | 1, 7 | 1 | 11, 20 | 11 | 7, 11, 12 | 11, 8, 14, 15–17, 19, 21 | 18 | |
| Ml | 11, 12 | 11, 19 | 18 | |||||
| NI | 4, 5, 10 | 2, 3, 4, 9, | 3, 6, 13 | 3, 6 | ||||
Data are mainly based on immunohistochemical and mRNA detection techniques. Childhood indicates the period from neonatal life to prepuberty. Adult indicates the period of life starting from peri puberty. ERα, estrogen receptors alpha; ERβ, estrogen receptors beta; Gc, granular cell; GPER-1, G protein estrogen receptors (G protein-coupled transmembrane receptors); Ml, molecular layer; NI, localization not identified (studies only based on mRNA detection techniques); PC, Purkinje cell. 1, Sakamoto et al., 2003 [84]; 2 Tabatadze et al., 2014 [66]; 3 Munetomo et al., 2015 [83]; 4 Lavaque et al., 2005 [81]; 5 Dean et al., 2012 [94]; 6 Abel et al., 2011 [95]; 7 Biamonte et al., 2009 [96]; 8 Andreescu et al., 2008 [97]; 9 Roselli et al. 1984 [82]; 10 Yamada et al. 1994 [98]; 11 Ikeda and Nakai 2006 [88]; 12 Jakab et al. 2001 [99]; 13 Mohamed et al., 2000 [100]; 14 Mitra et al., 2003 [89]; 15 Price and Handa et al. 2000 [90]; 16 Shughrue et al. 1997 [101]; 17 Zhang et al. 2002 [102]; 18 Hazell et al., 2009 [29]; 19 Cardona-Gomez et al. 2000 [103]; 20 Perez et al. 2003 [104]; 21 Shughrue and Merchenthaler 2001 [105]. See the text for detail.