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. 2020 May 2;21(9):3233. doi: 10.3390/ijms21093233
ABC ATP-binding cassette
ATR Ataxia telangiectasia and Rad3-related protein
5-FU 5-Fluorouracil
BCRP Human breast cancer resistance protein
BBB Blood–brain barrier
BRCA Breast cancer gene
CAF Chromatin assembly factor-1
CD24 Glycosylphosphatidylinositol-linked cell surface glycoprotein gene
CDK 4/6 Cyclin-dependent kinase 4/6
CML Chronic myeloid leukemia
CYP Cytochrome
DDR DNA-damage response
DDRNAs DNA damage response RNAs
decitabine; DAC 5-Aza-2′-deoxycytidine
DNA-PKc DNA-dependent protein kinase
DOX Doxorubicin
DPDs Dihydropyrimidine dehydrogenases
DSB Double-strand break
ECM Extracellular matrix
EOC Epithelial ovarian cancer
FBW7 F-box and WD repeat domain-containing 7 protein
FBX8 F-box only protein 8
FDA U.S. Food and Drug Administration
FEN-1 Flap structure-specific endonuclease 1
FGF Fibroblast growth factor
GSAO 4-(N-(S-glutathionylacetyl)amino)phenylarsonous acid
GSH Glutathione
GSTs Glutathione-S-transferases
HER2 Human epidermal growth factor receptor-2 gene
hMLH1 Human MutL homolog 1 gene
HR Homologous recombination
IC50 Half-maximum inhibitory concentration
ICLs Interstrand DNA cross-links
iDNMT DNA methylation inhibitor
iHDAC Histone deacetylase inhibitor
iso-PXA Iso-pencillixanthone A
LQTS Long QT syndrome
MAPK Mitogen-activated protein kinase
Mcl-1 Induced myeloid leukemia cell differentiation protein
MDR Multidrug resistance
MMP Matrix metalloproteinase
MMR Mismatch repair
mPEG Methoxypolyethylene glycol
NER Nucleotide excision repair
NHEJ Nonhomologous end joining pathway
NSCLC Non-small cell lung cancer
PARP Poly (ADP-ribose) polymerase protein
PCNA Lys-164-mono-ubiquitinated proliferating cell nuclear antigen
P-gp; ABCB1 P-glycoprotein; ATP-binding cassette subfamily B member 1
ROS Reactive oxygen species
RPA Replication protein A
RTK Receptor tyrosine kinase
SCF SKP1-CUL1-F-box
SCLC Small cell lung cancer
SNP Single nucleotide polymorphism
ssDNA Single-strand DNA
T2AA T2 amino alcohol
TAM Tumor-associated macrophage
TCGA The Cancer Genome Atlas
TiO2 PEG NP Polyethylene glycol-modified titanium dioxide nanoparticle
TLS Translesion synthesis
TPMTs Thiopurine methyltransferases
TRAIL Tumor necrosis factor-related apoptosis-inducing ligand
TTM Tometodione M
UGTs Uridine diphospho-glucuronosyltransferases
VCR Vincristine
VEGF-A Vascular endothelial growth factor A
γGTs Gamma-glutamyl transferases