APE1 |
apurinic/apyrimidinic endonuclease 1 |
BER |
base excision repair |
AP site |
apurinic/apyrimidinic site |
SSB |
single-strand break |
Polβ |
DNA polymerase β |
XRCC1 |
X-ray repair cross-complementing protein 1 |
PARP1 |
poly(ADP-ribose) polymerase 1 |
APE1NΔ35/APE1NΔ61 |
APE1 without 35/61 N-terminal amino acid residues |
FAM |
5(6)-carboxyfluorescein |
TMR |
5(6)-carboxytetramethylrhodamine |
FRET |
Fluorescence resonance energy transfer |
AP-DNA/gap-DNA |
DNA with a synthetic AP site/1-nucleotide gap |
FAM-SE/TMR-SE |
succinimidyl ester of 5(6)-carboxyfluorescein/5(6)-carboxytetramethylrhodamine |