Aβ	β-Amyloid
Aβ1-40	The 40 amino acid isoform of amyloid β
Aβ1-42	The 42 amino acid isoform of amyloid β
AD	Alzheimer’s disease
APP	Amyloid-β protein precursor
BACE1	β-secretase
BBB	Blood–brain barrier
CNS	Central nervous system
CSF	Cerebral spinal fluid
EVs	Extracellular vesicles
FDG-PET	Fluorodeoxyglucose-positron emission tomography
GFAP	Glial fibrillary acidic protein
IWG	International working group
MCI	Mild cognitive impairment
miRNA	MicroRNA
MRI	Magnetic resonance imaging
NfL	Neurofilament light
NFT	Neurofibrillary tau tangles
NIA-AA	National Institute on Aging and Alzheimer’s Association
OS	Oxidative stress
PET	Positron emission tomography
PSEN1	Presenilin 1
PSEN2	Presenilin 2
P-tau	Phosphorylated tau
SNAP-25	Synaptosomal nerve-associated protein 25
T-tau	Total tau
WT	Wildtype
YKL-40	Chitinase-3-like protein 1 (CHI3L1), also known as YKL-40