Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Metformin action on mitochondrial homeostasis. Metformin acts on mitochondrial homeostasis by two pathways: on one side it increases mitochondrial biogenesis and induces mitochondrial fusion via PGC-1α activation. On the other side it induces the formation of autophagosomes and promotes the clearance of damaged mitochondria via mTOR inhibition.
