AOP |
Adverse Outcome Pathway |
DIO |
Deiodinase |
ECHA |
European Chemicals Agency |
ECVAM |
European Centre for the Validation of Alternative Methods |
EFSA |
European Food Safety Authority |
EOGRTS |
Extended One-Generation Reproductive Toxicity Study |
HTS |
High Throughput Screening |
EROD |
7-Ethoxyresorufin O-dealkylase |
IYD |
Iodotyrosine dehalogenase 1 |
MCT8 |
Monocarboxylate transporter 8 |
MOA |
Mode of Action |
NIS |
Sodium iodide symporter |
OECD |
Organisation for Economic Cooperation and Development |
PROD |
Pentoxyresorufin O-dealkylase |
QSAR |
Quantitative Structure–Activity Relationship |
T3 |
Triiodothyronine |
T4 |
Thyroxine |
TBG |
Thyroxin-Binding Globulin |
TG |
Test Guideline |
TR |
Thyroid Receptor |
TRH |
Thyrotropin-Releasing Hormone |
TSH |
Thyroid Stimulating Hormone |
TSHR |
Thyroid Stimulating Hormone Receptor |
TTR |
Transthyretin |
UDPGT |
Uridine 5′diphospho-glucuronosyltransferase |